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Bing Chen Selected Research

Bortezomib (Velcade)

1/2022Solamargine induces autophagy-mediated apoptosis and enhances bortezomib activity in multiple myeloma.
10/2021DKK1 suppresses WWP2 to enhance bortezomib resistance in multiple myeloma via regulating GLI2 ubiquitination.
1/2021Bortezomib activation of mTORC1 pathway mediated by NOX2-drived reactive oxygen species results in apoptosis in primary dorsal root ganglion neurons.
9/2019A randomized phase II, open-label and multicenter study of combination regimens of bortezomib at two doses by subcutaneous injection for newly diagnosed multiple myeloma patients.
9/2019Higher single dose of bortezomib plus thalidomide and dexamethasone is a promising therapy for newly diagnosed multiple myeloma.
1/2019Prognostic Value of 1q21 Gain in Multiple Myeloma.

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Bing Chen Research Topics

Disease

125Neoplasms (Cancer)
08/2022 - 06/2003
33Spinal Cord Injuries (Spinal Cord Injury)
03/2022 - 06/2006
31Infections
12/2022 - 06/2006
31Breast Neoplasms (Breast Cancer)
06/2022 - 01/2012
27Neoplasm Metastasis (Metastasis)
08/2022 - 08/2004
21Inflammation (Inflammations)
06/2022 - 05/2002
21Wounds and Injuries (Trauma)
12/2021 - 08/2002
19Carcinogenesis
08/2022 - 12/2010
18Tuberculosis (Tuberculoses)
01/2018 - 09/2002
14Hypoxia (Hypoxemia)
01/2022 - 12/2007
14Leukemia
01/2021 - 12/2004
13Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2009
12COVID-19
01/2022 - 01/2020
11Multiple Myeloma
01/2022 - 11/2018
10Hepatocellular Carcinoma (Hepatoma)
03/2021 - 08/2004
10Myocardial Infarction
12/2019 - 02/2005
9Cicatrix (Scar)
01/2022 - 04/2009
9Obesity
01/2022 - 02/2012
9Pain (Aches)
01/2021 - 12/2002
9Type 2 Diabetes Mellitus (MODY)
01/2018 - 01/2011
9Insulin Resistance
01/2017 - 07/2011
8Hematologic Neoplasms (Hematological Malignancy)
07/2022 - 01/2016
8Fibrosis (Cirrhosis)
05/2022 - 08/2014
8Colorectal Neoplasms (Colorectal Cancer)
08/2021 - 06/2014
8Lymphoma (Lymphomas)
04/2021 - 01/2015
8Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2020 - 07/2014
8Ischemia
01/2016 - 03/2009
7Thrombosis (Thrombus)
10/2022 - 04/2013
7Body Weight (Weight, Body)
10/2021 - 06/2007
7Stomach Neoplasms (Stomach Cancer)
01/2021 - 05/2010
6Hearing Loss (Hearing Impairment)
06/2022 - 08/2011
6Hemorrhage
05/2022 - 08/2012
6Adenocarcinoma of Lung
01/2022 - 09/2019
6Glioma (Gliomas)
01/2022 - 06/2003
6Lung Neoplasms (Lung Cancer)
01/2022 - 12/2015
6Stroke (Strokes)
10/2021 - 01/2006
6Hypertension (High Blood Pressure)
01/2021 - 07/2013
6Acute Promyelocytic Leukemia
01/2021 - 05/2002
6Sepsis (Septicemia)
01/2021 - 01/2011
6Colonic Neoplasms (Colon Cancer)
01/2020 - 07/2006
6Ulcer
12/2019 - 10/2007
6Diabetic Foot
10/2018 - 01/2011
5Peripheral Nervous System Diseases (PNS Diseases)
01/2022 - 09/2014
5Triple Negative Breast Neoplasms
01/2022 - 01/2019
5Thyroid Diseases (Thyroid Disease)
01/2021 - 07/2010
5Carcinoma (Carcinomatosis)
11/2020 - 03/2009
5Deafness (Deaf Mutism)
11/2020 - 07/2012
5Diabetes Mellitus
01/2020 - 02/2008

Drug/Important Bio-Agent (IBA)

55Proteins (Proteins, Gene)FDA Link
08/2022 - 06/2003
45CollagenIBA
12/2022 - 11/2006
33Pharmaceutical PreparationsIBA
01/2022 - 10/2002
25Biomarkers (Surrogate Marker)IBA
01/2022 - 12/2008
19Long Noncoding RNAIBA
06/2022 - 11/2017
19VaccinesIBA
10/2020 - 10/2002
18MicroRNAs (MicroRNA)IBA
12/2021 - 09/2012
17Circular RNAIBA
05/2022 - 04/2016
15Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 04/2009
12RNA (Ribonucleic Acid)IBA
06/2022 - 01/2015
12Messenger RNA (mRNA)IBA
01/2022 - 05/2010
12Biological ProductsIBA
01/2022 - 12/2004
12Glucose (Dextrose)FDA LinkGeneric
01/2022 - 11/2012
12CytokinesIBA
12/2021 - 07/2010
9Doxorubicin (Adriamycin)FDA LinkGeneric
07/2022 - 07/2014
9DNA (Deoxyribonucleic Acid)IBA
03/2022 - 06/2003
9AntibodiesIBA
01/2022 - 03/2008
9LipidsIBA
01/2022 - 06/2006
9Insulin (Novolin)FDA Link
11/2018 - 12/2007
8AntigensIBA
05/2022 - 03/2013
8Indicators and Reagents (Reagents)IBA
01/2022 - 03/2011
8EnzymesIBA
01/2022 - 07/2006
7TamoxifenFDA LinkGeneric
01/2022 - 01/2019
7Hemoglobins (Hemoglobin)IBA
01/2022 - 07/2013
7IodineIBA
12/2021 - 01/2019
7Therapeutic UsesIBA
11/2021 - 08/2007
7oxidized low density lipoproteinIBA
01/2021 - 08/2013
7Interleukin-6 (Interleukin 6)IBA
11/2020 - 07/2010
7Brain-Derived Neurotrophic Factor (BDNF)IBA
06/2015 - 10/2009
6AutoantibodiesIBA
01/2022 - 01/2015
6Bortezomib (Velcade)FDA Link
01/2022 - 01/2019
6LipopolysaccharidesIBA
11/2021 - 06/2009
6Biocompatible Materials (Biomaterials)IBA
07/2021 - 08/2002
6EpitopesIBA
03/2021 - 12/2010
6Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
12/2019 - 09/2007
6CreatinineIBA
02/2019 - 04/2007
5Cisplatin (Platino)FDA LinkGeneric
08/2022 - 12/2015
5Transcription Factors (Transcription Factor)IBA
01/2021 - 11/2012
5ErbB Receptors (EGF Receptor)IBA
01/2021 - 07/2015
5Metformin (Glucophage)FDA LinkGeneric
01/2021 - 09/2012
5Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2021 - 05/2002
5Glycoproteins (Glycoprotein)IBA
01/2021 - 02/2005
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2019 - 10/2007

Therapy/Procedure

79Therapeutics
10/2022 - 05/2002
24Drug Therapy (Chemotherapy)
07/2022 - 10/2003
22Transplantation
03/2022 - 06/2006
11Radiotherapy
12/2019 - 06/2009
9Hematopoietic Stem Cell Transplantation
10/2020 - 07/2006
8Immunotherapy
01/2022 - 01/2016
6Stents
01/2022 - 08/2008
5Length of Stay
01/2022 - 03/2013
5Cochlear Implantation
11/2020 - 08/2011